Anchored HTML File of EIDs

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway Name:Wnt signaling pathway ID:04310
C=150; O=4; E=0.11; R=37.10; rawP=4.11e-06; adjP=2.06e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000139174	NA	PRICKLE1	prickle homolog 1 (Drosophila)	144165	ENSG00000139174
2	ENSG00000104332	NA	SFRP1	secreted frizzled-related protein 1	6422	ENSG00000104332
3	ENSG00000143816	NA	WNT9A	wingless-type MMTV integration site family, member 9A	7483	ENSG00000143816
4	ENSG00000157240	NA	FZD1	frizzled family receptor 1	8321	ENSG00000157240

Database:KEGG pathway Name:Basal cell carcinoma ID:05217
C=55; O=2; E=0.04; R=50.59; rawP=0.0007; adjP=0.0018
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000143816	NA	WNT9A	wingless-type MMTV integration site family, member 9A	7483	ENSG00000143816
2	ENSG00000157240	NA	FZD1	frizzled family receptor 1	8321	ENSG00000157240

Database:KEGG pathway Name:Pathways in cancer ID:05200
C=326; O=3; E=0.23; R=12.80; rawP=0.0016; adjP=0.0027
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000143816	NA	WNT9A	wingless-type MMTV integration site family, member 9A	7483	ENSG00000143816
2	ENSG00000156427	NA	FGF18	fibroblast growth factor 18	8817	ENSG00000156427
3	ENSG00000157240	NA	FZD1	frizzled family receptor 1	8321	ENSG00000157240

Database:KEGG pathway Name:Melanogenesis ID:04916
C=101; O=2; E=0.07; R=27.55; rawP=0.0024; adjP=0.0030
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000143816	NA	WNT9A	wingless-type MMTV integration site family, member 9A	7483	ENSG00000143816
2	ENSG00000157240	NA	FZD1	frizzled family receptor 1	8321	ENSG00000157240

Database:KEGG pathway Name:Metabolic pathways ID:01100
C=1130; O=2; E=0.81; R=2.46; rawP=0.1947; adjP=0.1947
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000172954	NA	LCLAT1	lysocardiolipin acyltransferase 1	253558	ENSG00000172954
2	ENSG00000086475	NA	SEPHS1	selenophosphate synthetase 1	22929	ENSG00000086475

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).